Professor Jude A Oben, is a Physician Scientist and holds a Consultant appointment in Gastroenterology and Hepatology at Guy’s & St Thomas’ Hospital, London. He was previously an Associate Professor in Hepatology, at University College London, Institute of Liver and Digestive Health. Prof Oben has a Ph.D in Pharmacology from University College London and studied medicine at Oxford University (St John’s College), with some time at Stanford University, Palo Alto, USA, as a Research Fellow in Immunology. After Oxford, his initial post-graduate medical training was at the Royal Post-Graduate Medical School, Imperial College London, after which he commenced specialist training in Ophthalmology (Eye Surgery) from which he changed to specialise in Gastroenterology-Hepatology.

During specialist registrar training in Gastroenterology-Hepatology, he re-orientated his research career with 2 years as a Post-Doctoral Fellow at Johns Hopkins University, Baltimore, USA. Prof Oben’s work at Johns Hopkins combined his previous interest in neuroscience with liver medicine and he published extensively on the interactions between the autonomic nervous system and liver repair via liver progenitor stem cells and liver stellate cells, in the context of Diabetic Liver Disease (Metabolic dysfunction-associated steatotic liver disease, MASLD). On the back of a very productive period at Johns Hopkins, he was awarded a Wellcome Trust Intermediate Fellowship funding on returning to London. His research has remained productive. He is a Fellow of the Royal College of Physicians of London and Edinburgh; an elected Fellow of the American Gastroenterological Association, and an elected Fellow of the American Association for the Study of Liver Diseases. He has also been elected to membership of Sigma Xi, the scientific research honour society.

Publications

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Clinical, experimental and pathophysiological effects of Yaq-001: a non-absorbable, gut-restricted adsorbent in models and patients with cirrhosis. Liu J, MacNaughtan J, Kerbert AJC, Portlock T, Martínez Gonzalez J, Jin Y, Clasen F, Habtesion A, Ji H, Jin Q, Phillips A, De Chiara F, Ingavle G, Jimenez C, Zaccherini G, Husi K, Rodriguez Gandia MA, Cordero P, Soeda J, McConaghy L, Oben J, Church K, Li JV, Wu H, Jalan A, Gines P, Solà E, Eaton S, Morgan C, Kowalski M, Green D, Gander A, Edwards LA, Cox IJ, Cortez-Pinto H, Avery T, Wiest R, Durand F, Caraceni P, Elosua R, Vila J, Pavesi M, Arroyo V, Davies N, Mookerjee RP, Vargas V, Sandeman S, Mehta G, Shoaie S, Marchesi J, Albillos A, Andreola F, Jalan R. Gut. 2024;73(7):1183-1198. doi: 10.1136/gutjnl-2023-330699.

The British Association for the Study of the Liver commitment to equality, diversity, and inclusivity. Jones R, Phillips S, Elsharkawy A, Singhal S, Leithead J, Chokshi S, Towey J, Subhani M, Wood C, Davidson K, Kooner E, Aithal G, Oben JA. Lancet Gastroenterol Hepatol. 2023;8(12):1066-1068. doi: 10.1016/S2468-1253(23)00322-9. Epub 2023 Oct 4.

Metabolic endoscopy and a simplified low-carbohydrate-high-dietary fiber template as novel treatments for hidradenitis suppurativa – A case series. Mandour MO, Al-Musawi S, Idowu E, Long PF, Rashidghamat E, Oben JA. JAAD Case Rep. 2023;34:23-26. doi: 10.1016/j.jdcr.2023.01.035. eCollection 2023 Apr.

A Meta-analysis on Associated Risk of Mortality in Nonalcoholic Fatty Liver Disease. Fu CE, Ng CH, Yong JN, Chan KE, Xiao J, Nah B, Bong SHS, Win KM, Bwa AH, Lim WH, Tan DJH, Zeng RW, Chew N, Teng MLP, Siddiqui MS, Oben JA, Sanyal AJ, Wong VW, Noureddin M, Muthiah M. Endocr Pract. 2023;29(1):33-39. doi: 10.1016/j.eprac.2022.10.007. Epub 2022 Oct 20.

Advancing the global public health agenda for NAFLD: a consensus statement. Lazarus JV, Mark HE, Anstee QM, Arab JP, Batterham RL, Castera L, Cortez-Pinto H, Crespo J, Cusi K, Dirac MA, Francque S, George J, Hagström H, Huang TT, Ismail MH, Kautz A, Sarin SK, Loomba R, Miller V, Newsome PN, Ninburg M, Ocama P, Ratziu V, Rinella M, Romero D, Romero-Gómez M, Schattenberg JM, Tsochatzis EA, Valenti L, Wong VW, Yilmaz Y, Younossi ZM, Zelber-Sagi S; NAFLD Consensus Consortium. Nat Rev Gastroenterol Hepatol. 2022;19(1):60-78. doi: 10.1038/s41575-021-00523-4. Epub 2021 Oct 27.

Non-alcoholic fatty liver disease: Is surgery the best current option and can novel endoscopy play a role in the future?. Mandour MO, El-Hassan M, Elkomi RM, Oben JA. World J Hepatol. 2022;14(9):1704-1717. doi: 10.4254/wjh.v14.i9.1704.

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